Aktuelle Publikationen

Richter L, Munter LM, Ness J, Hildebrand PW, Dasari M, Unterreitmeier S, Bulic B, Beyermann M, Gust R, Reif B, Weggen S, Langosch D, Multhaup G. Amyloid beta 42 peptide Abeta42-lowering compounds directly bind to Abeta and interfere with amyloid precursor protein (APP) transmembrane dimerization. Proc Natl Acad Sci U S A. 2010 Aug 17;107(33):14597-602.

Korshunov A, Remke M, Werft W, Benner A, Ryzhova M, Witt H, Sturm D, Wittmann A, Schöttler A, Felsberg J, Reifenberger G, Rutkowski S, Scheurlen W, Kulozik AE, von Deimling A, Lichter P, Pfister SM.Adult and pediatric medulloblastomas are genetically distinct and require different algorithms for molecular risk stratification. J Clin Oncol. 2010 Jun 20;28(18):3054-60.

Giles K, Glidden DV, Patel S, Korth C, Groth D, Lemus A, DeArmond SJ, Prusiner SB. Human prion strain selection in transgenic mice. Ann Neurol. 2010 Aug;68(2):151-61

Seshadri S, Kamiya A, Yokota Y, Prikulis I, Kano SI, Hayashi-Takagi A, Stanco A, Eom TY, Rao S, Ishizuka K, Wong P, Korth C, Anton ES, Sawa A. Disrupted-in-Schizophrenia-1 expression is regulated by beta-site amyloid precursor protein cleaving enzyme-1-neuregulin cascade. Proc Natl Acad Sci U S A. 2010 Mar 8. Epub ahead of print

Hu W, Nessler S, Hemmer B, Eagar TN, Kane LP, Leliveld SR, Müller-Schiffmann A, Gocke AR, Lovett-Racke A, Ben LH, Hussain RZ, Breil A, Elliott JL, Puttaparthi K, Cravens PD, Singh MP, Petsch B, Stitz L, Racke MK, Korth C, Stüve O. Brain. Pharmacological prion protein silencing accelerates central nervous system autoimmune disease via T cell receptor signalling. 2010 Feb;133(Pt 2):375-88.

Weller M, Stupp R, Reifenberger G, Brandes AA, van den Bent MJ, Wick W, Hegi ME. MGMT promoter methylation in malignant gliomas: ready for personalized medicine? Nat Rev Neurol. 2010 Jan;6(1):39-51.

Waha A, Felsberg J, Hartmann W, von dem Knesebeck A, Mikeska T, Joos S, Wolter M, Koch A, Yan PS, Endl E, Wiestler OD, Reifenberger G, Pietsch T, Waha A. Epigenetic downregulation of mitogen-activated protein kinase phosphatase MKP-2 relieves its growth suppressive activity in glioma cells. Cancer Res. 2010 Feb 15;70(4):1689-99.

Pfister S, Remke M, Benner A, Mendrzyk F, Toedt G, Felsberg J, Wittmann A, Devens F, Joos S, Kulozik A, Reifenberger G, Rutkowski S, Wiestler OD, Radlwimmer B, Scheurlen W, Lichter P, Korshunov A. Molecular risk stratification of pediatric medulloblastoma based on genomic aberrations. J Clin Oncol 2009 Mar 2. Epub ahead of print .

Glas M, Happold C, Rieger J, Wiewrodt D, Bähr O, Steinbach JP, Wick W, Kortmann RD, Reifenberger G, Weller M, Herrlinger U. Long-term survival of glioblastoma patients treated with radiotherapy and lomustine plus temozolomide. J Clin Oncol 2009 Feb 2. Epub ahead of print

Stuve O, Korth C, Gabatto P, Cameron EM, Hu W, Eagar TN, Monson NL, Frohman EM, Racke MK, Zabetian CP, Oksenberg JR. Genetic polymorphism at codon 129 of the prion protein is not associated with multiple sclerosis. Arch Neurol 2009 Feb;66(2):280-1.

Singh MP, Meyer zu Horste G, Hu W, Mausberg A, Cravens P, Eager T, Löber S, Klingenstein R, Gmeiner P, Korth C, Kieseier BC, Stüve O. Quinpramine is a novel compound effective in ameliorating brain autoimmune disease.. Exp Neurol 2009 Feb;215(2):397-400

Müller-Schiffmann A, Petsch B, Leliveld SR, Muyrers J, Salwierz A, Mangels C, Schwarzinger S, Riesner D, Stitz L, Korth C. Complementarity determining regions of a funtional anti-PrP scFv orchestrate conformation-specificity and antiprion activity. Mol Immunol 2009 Feb;46(4):532-40

Kummer MP, Maruyama H, Huelsmann C, Baches S, Weggen S, Koo EH. Formation of PMEL17 amyloid is regulated by juxtamembrane metalloproteinase cleavage and the resulting C-terminal fragment is a substrate for gamma-secretase. J Biol Chem. 2009 Jan 23;284(4):2296-306

Koga T, Morita A, Maruyama K, Tanaka M, Ino Y, Shibahara J, Louis DN, Reifenberger G, Itami J, Hara R, Saito N, Todo T. Long-term control of disseminated pleomorphic xanthoastrocytoma with anaplastic features by means of stereotactic irradiation. Neuro Oncol. 2009 Jan 22. Epub ahead of print

Warnke C, Lanzman RS, Klink B, Schellhammer F, Reifenberger G, Methner A (2008) Diffuse leptomeningeal astrocytoma in a patient suffering from infantile epilepsy. Arch Neurol. 2009 Mar;66(3):408-9.

Scholz M, Hoischen A, Radlwimmer B, Weber RG, Harders A, Reifenberger G, Riemenschneider MJ. Rosetted glioneuronal tumor of the spine with overtly anaplastic histological features.Acta Neuropathol. 2009 May;117(5):591-3.

Riemenschneider MJ, Reifenberger G. Molecular diagnostics of gliomas. Int J Mol Sci 2009: 10: 184-212.

Riemenschneider MJ, Reifenberger G. Astrocytic tumors. Recent Results Cancer Res. 2009;171:3-24.